D Determination of Alkaloid Content of Kaluan Leaves (Vitex pinnata L.) With Different Fraction Levels

Authors

  • Rahmad Ismiadi Universitas sari Mulia Banjarmasin
  • Rohama Rohama Sari Mulia University
  • Melviani Melviani Sari Mulia University
  • Dede Mahdiyah Sari Mulia University

DOI:

https://doi.org/10.33859/jpcs.v5i1.657

Keywords:

Kaluan Leaves (Vitex pinnata L.), Total Alkaloid Content, Fraction Level

Abstract

Background: One of the plants that is often used by people in the interior of Central Kalimantan is the kaluan or halaban plant, where the kaluan or halaban plant is a typical Kalimantan plant that Dayak people usually know as laban. The Kaluan plant is often used by the community as a natural treatment. Kaluan leaves are generally used to treat wounds, scabies, and relieve fever. Kaluan plants have chemical content, the leaves and stem bark contain relatively large amounts of alkaloids, flavonoids, saponins, sterolterpenoids and tannins, which are active compounds that can ward off free radicals.
Objective: This research aimed to determine the alkaloid levels in calluan plants (Vitex pinnata L) using fraction levels, distilled water, chloroform, n-hexane.
Methods: This research uses an experimental method using the True Experimental type of research which aims to see the comparison of alkaloid levels from kaluan leaf extract (Vitex pinnata Linn) when using N-hexane, chloroform and methanol fractions. The research design used in this study was Randomized block design (random sampling) and compared samples with the 3 fractions used (N-hexane, chloroform, and distilled water).
Results: Based on the research that has been carried out, it can be concluded that the total alkaloid content in each, namely, for the n-hexane fraction is 8.03%, for the chloroform fraction it is 7.1%, and for the distilled water fraction it is 2.41%.
Conclusion: Based on research, the highest alkaloid content was in the n-hexane fraction, namely 8.03%

References

Abriyani, E., Putri, N.S. ., Rosidah, R.S.N., & Ismanita, S.S. (2022). Analisis Kafein Menggunakan Metode Uv-Vis: Tinjauan Literatur. Jurnal Pendidikan Dan Konseling (JPDK), 4(6).

Alimah, D. (2020). Characteristics and Cultivation of Laban (Vitex pubescens) for Energy Wood Purpose. Prosiding Seminar Nasional Lingkungan Lahan Basah, 5(April), 74–79.

Badaring, D. R., Puspitha, S., Sari, M., Nurhabiba, S., Wulan, W., Anugrah, S., Lembang, R., dan Biologi, J. (2020). Uji Ekstrak Daun Maja (Aegle marmelos L.) terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus INDONESIAN JOURNAL OF FUNDAMENTAL SCIENCES (IJFS). Indonesian Journal of Fundamental Sciences, 6(1).

Datak, G., Didin Ardiyani, V., & Diang Mahalia, L. (2020). Formulasi Sediaan Krim Ekstrak Daun Dan Kulit Batang Kalapapa (Vitex Pinnata L.) Sebagai Obat Penyembuhan Luka.

Evifania, R.D., Apridamayanti, P., Sari, R. (2020). Uji parameter spesifik dan nonspesifik simplisia daun senggani (Melastoma malabathricum L.). Jurnal Cerebellum, 6(1).

Fakri, F., Illian, D. N., Desiyana, L. S., Isnaini, N., & Muhni, A. (n.d.). Aktivitas Antibakteri Ekstrak Metanol Daun Vitex pinnata L. terhadap Staphylococcus aureus. http://www.jurnal.unsyiah.ac.id/bioleuser

Fatimah, F., Lestariningsih, N., Najwa, F., Ainullatiffah, N., dan Dalila, A. (2023). Pemanfaatan Tumbuhan Halaban (Vitex pinnata) Sebagai Obat Herbal Bagi Masyarakat Kalimantan Tengah. Jurnal Penelitian Sains Dan Pendidikan (JPSP), 3(1), 65–72. https://doi.org/10.23971/jpsp.v3i1.6034

Fatimah, Meiana, N. A., Najwa, F., Ainullatiffah, N., Dalila, A., dan Lestariningsih, N. (2023). Pemanfaatan Tumbuhan Halaban (Vitex pinnata) Sebagai Obat Herbal Bagi Masyarakat Kalimantan Tengah. https://e-journal.iain-palangkaraya.ac.id/index.php/mipa/

Fujianti, H. (2021). Pemanfaatan Tanaman Berkhasiat Obat Diabetes Mellitus Suku Dayak Ngaju Ditumbang Samba Kalimantan Tengah Sebagai Buku Referensi Botani. IAIN Palangkaraya.

Hati, A.K., Multazamudin, Iqbal, M. (2018). Uji Aktivitas Antibakteridan Kandungan Senyawa AktifEkstrak n-Heksan,Etil Asetat dan Etanol 70% biji Melinjo (Gnetum gnemon. L). Indonesian Journal of Pharmacy and Natural Product, 1(1).

LIPI. (2019). Peraturan Lembaga Ilmu Pengetahuan Indonesia tentang Klirens Etik Penelitian.

Mastura, M., Barus, T., Marpaung, L., dan Simanjuntak, P. (2019). Aktivitas Antioksidan Dan Toksisitas Fraksi Etil Asetat Dari Daun Halban (Vitex Pinnata Linn) Asal Aceh. Talenta Conference Series: Science and Technology (ST), 2(1), 45–51. https://doi.org/10.32734/st.v2i1.310

Mujipradhana, V.N., Wewengkang, D., dan Suryanto, E. (2018). Aktivitas Antimikroba Dari Ekstrak Ascidian Herdmania momus Pada Mikroba Patogen Manusia. PHARMACON: Jurnal Ilmiah Farmasi, 7(1).

Rahmah, N., Rohama, dan Melviani. (2023). Penetapan Kadar Alkaloid Total Ekstrak Daun Rambusa (Passiflora foetida L.) dengan Tingkatan Fraksi. In Sains Medisina (Vol. 1, Issue 4).

Ramadhani, M.A, Hati, A.K., dan Lukitasari, N.F. (2020). Skrining Fitokimia Dan Penetapan Kadar Flavonoid Total Serta Fenolik Total Ekstrak Daun Insulin (Tithonia diversifolia) Dengan Maserasi Menggunakan Pelarut Etanol 96 %. Indonesian Journal of Pharmacy and Natural Product, 3(1).

Saputri, R., dan Hakim, A. R. (2021). Metodologi Penelitian Kesehatan (Vol. 1).

Wahyuni, R., dan Rivai, H. (2014). Pengaruh Cara Pengeringan dengan Oven, Kering Angin dan Cahaya Matahari Langsung Terhadap Mutu Simplisia Herba Sambiloto. In Jurnal Farmasi Higea (Vol. 6, Issue 2).

Wahyuni, S., dan Marpaung, M. (2020). Penentuan Kadar Alkaloid Total Ekstrak Akar Kuning (Fibraurea chloroleuca Miers) Berdasarkan Perbedaan Konsentrasi Etanol Dengan Metode Spektrofotometri UV-VIS. Dalton: Jurnal Pendidikan Kimia dan Ilmu Kimia, 3(2).

Winahyu, D.A., Retnaningsih, A., dan Aprillia, M. (2019). Determination Of Flavonoid Levels In Raru Wood Stone (CotylelobiummelanoxylonP) With Method Uv-Vis Spectrofotometry. Jurnal Analis Farmasi, 4(1).

Najib, A., Malik, A., Ahmad, A.R., Handayani, V., Syarif, R.A., Waris, R. (2017). Standarisasi Ekstrak Air Daun Jati Belanda dan Teh Hijau. Jurnal Fitofarmaka Indonesia, 2 (1), 241-245.

Saidi, S.A., Slimene, M.B., Khilfi,, M.A. (2018). Transient Stability Analysis of Photovoltaic System with Experimental Shading Effects. Engineering, Technology, and Applied Science Research, 8(6).

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Published

2024-12-02

How to Cite

Ismiadi, R., Rohama, R., Melviani, M., & Mahdiyah, D. (2024). D Determination of Alkaloid Content of Kaluan Leaves (Vitex pinnata L.) With Different Fraction Levels. Journal Pharmaceutical Care and Sciences, 5(1), 84–92. https://doi.org/10.33859/jpcs.v5i1.657

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