S Studi In Vitro Perbedaan Pelarut Pada Membran Selulosa Tandan  Kosong Kelapa Sawit (TKKS) Terhadap Penurunan Kreatinin

Tri Dewi Jayanti; Nur Hidayah; Putri Vidiasari Darsono; Tuti Alawiyah

doi:10.33859/jpcs.v5i1.668

Authors

Tri Dewi Jayanti Universitas Sari Mulia
Nur Hidayah Universitas Sari Mulia
Putri Vidiasari Darsono Universitas Sari Mulia
Tuti Alawiyah Universitas Sari Mulia

DOI:

https://doi.org/10.33859/jpcs.v5i1.668

Keywords:

Cellulose, Creatinine, DMAc, Membrane, NMP, Spectrophoyometry

Abstract

Background: Technology membrane the more develop be one application important in field biomedicine that is dialysis in the hemodialysis process. Instrument dialysis use membrane fiber hollow made of from polymer synthesis so that the price is expensive and in Indonesia the technology This Still left behind Far. Therefore That need alternative in availability membrane as material making membrane. One of them utilise cellulose from TKKS waste.
Objective: To determine the effectiveness of solvent variations in TKKS cellulose membranes in reducing creatinine levels in vitro.
Methods: Cross sectional analytical observation. Quantitative testing uses Uv-Vis Spectrophotometry.
Results: Membranes with a variety of solvents can reduce creatinine levels, i.e membrane more DMAc solvent effective lower rate creatinine at each cycle with rate initial 3 mg/dL, time every cycle 3 minutes 55 seconds. DMAc membrane capable lower rate every cycle namely 0,509 mg/dL, 0,486 mg/dL, 0,476 mg/dL, and 0,463 mg/dL.
Conclusion: Membrane TKKS uses cellulose more DMAc solvent effective in lower rate creatinine. So that need done study more carry on in its application in the health sector.

References

Amilia, Z., Muhdarina, L., Kimia, J., Matematika, F., Riau, U., Bina, K., & Panam, W. (2013). Pembuatan Membran Hibrid Polisulfon-Lempung Yang Dikoagulasi Oleh 2-Propanol-Air Dan Aplikasinya Pada Air Gambut. In Jurnal Photon (Vol. 4, Issue 1).

Amri, C. (2015). Study Of Preparation And Characterization Of Esterified Alginate As Hemodialysis Membrane.

Apriani, R., Rohman, T., & Mustikasari, K. (2018). Sintesis dan Karakterisasi Membran Selulosa Asetat dari Tandan Kosong Kelapa Sawit. Jurnal Riset Industri Hasil Hutan, 9 No.2, 91–98.

Ariadi Lusiana, R., & Basid Adi, N. (2020). Membran dan Aplikasinya (I). CV.Tigamedia Pratama.

Ayu Prestisya, I. (2016). Pembuatan Dan Karakterisasi Membran Nanofiber Selulosa Asetat Dengan Teknik Electrospinning Sebagai Hemodialisis Kreatinin.

Citra Lestari, W., Sukma Ningtiar, E., Irianto, M. Y., & Widiastuti, N. (2021). SPECTA Journal of Technology Review: Potensi Pengembangan Membran Polimer Hidrofilik untuk Produksi Biodiesel Berbasis Mikroalga. SPECTA Journal of Technology, 5, 115–122. https://journal.itk.ac.id/index.php/sjt

Faizal, M., Kimia Industri, T., Kimia, T., & Negeri Sriwijaya Jl Srijaya Negara Bukit Besar Palembang, P. (2022). Sintesis Dan Karakterisasi Selulosa Aasetat Dari Tandan Kosong Kelapa Sawit Sebagai Bahan Baku Bioplastik.

Grzybek, P., Dudek, G., & van der Bruggen, B. (2024). Cellulose-based films and membranes: A comprehensive review on preparation and applications. In Chemical Engineering Journal (Vol. 495). Elsevier B.V. https://doi.org/10.1016/j.cej.2024.153500

Hidayah, N. (2019). Studi Pendahuluan Potensi Limbah Tandan Kosong Kelapa Sawit Dalam Bidang Farmasi Dan Kesehatan. Jurnal Budidaya Tanaman Perkebunan Politeknik Hasnur, 05, 1–8.

Maghfiroh, D., Monica, E., & Afthoni, M. H. (2022). Pengembangan Dan Validasi Metode Spektrofotometri Uv Vis Metode Derivatif Untuk Analisis Kafein Dalam Suplemen. Sainsbertek Jurnal Ilmiah Sains & Teknologi, 2(2).

Permana, H. A., Delvitasari, F., Hartari, W. R., & Maryanti, M. (2024). Pengaruh Konsentrasi NaOH dan Suhu Delignifikasi pada Kandungan Lignoselulosa Tandan Kosong Kelapa Sawit. Jurnal Agro Industri Perkebunan, 51–58. https://doi.org/10.25181/jaip.v12i1.2729.

Sembiring, B. M. (2023). Analisis Secara Simultan Kandungan Metformin HCl Dan Glibenklamid Dalam Sediaan Tablet Secara Spektorfotometri Ultraviolet. Biologi Education Science & Tecnology Journal, 6(1), 704–710.

Zulfi, F., Dahlan, K., & Sugita, P. (2014). Karakteristik Fluks Membran Dalam Proses Filtrasi Limbah Cair Industri Pelapisan Logam. Jurnal Biofisika, 10, 19–29.