C Current Treatment and Primary Prophylaxis for Toxoplasmosis

Authors

  • Reqgi First Trasia Universitas Sultan Ageng Tirtayasa

DOI:

https://doi.org/10.33859/jpcs.v2i1.73

Keywords:

Treatment, Prophylaxis Toxoplasmosis

Abstract

Background: Toxoplasmosis is still a health problem in the world. This parasite is found cosmopolitan in humans and animals. In Indonesia, the prevalence of positive anti-Toxoplasma gondii substances in humans ranges from 2-63%, but there are still few comprehensive studies on current treatment and prophylaxis to treat it.

Objective: This article will provide an in-depth review of current treatment and primary prophylaxis in toxoplasmosis.

Methods: Searching the latest literature, obtained 10 relevant journals.

Results: Initial therapy Pyrimethamine 200 mg was given for 6 weeks. Maintenance therapy (suppressive, secondary prophylaxis) is given for life if immune reconstitution does not occur. Primary prophylaxis against toxoplasmic encephalitis is given to patients who are seropositive for Toxoplasma.

Conclusion: Initial therapy, maintenance, and primary prophylaxis can be useful to prevent worsening of the prognosis of toxoplasmosis disease.

References

Montoya JG, Liesenfeld O. [2008] Toxoplasmosis. Lancet 363:1965-76Obata K. [2009] Phylum apicomplexa: gregarines, coccidian, and relatedorganisms. In: Schmidt GD, Roberts LS (Eds). Foundation of Parasitology.7thedition. New York: Mc Graw Hill. p123-46Mamidi A, DeSimone JA, Pomerantz RJ. [2006] Central nervous system infections in individual with HIV-1 infection. Journal of Neuro Virology; 8:158-67Duval X, Leport C. [2004] Toxoplasmosis in AIDS. Current treatment options in infectious disease; 3:113-28Nath A, Sinai A. [2005] Cerebral toxoplasmosis. Current treatment options in infectious disease; 3:471-80Espinoza La. [2010] HIV/AIDS primary care guide. Toxoplasmosis. Florida/Caribbean AIDS education and training center: 11-4Frankel JK. [2002] In: Gilles HM (Ed). Protozoal disease. New York: Oxford University Press Inc.p.530-47Nicolle, Manceaux. [2003] Toxoplasma gondii. In: DespommierDD, Gwadz RW, Hotez PJ, Knirsch CA (Eds). Parasitic disease, 4thed. New York: Apple Tree production; p68-76Dubey JP, Beattie CP. [2001] Toxoplasmosis of animals and man. Florida; CRC Press, Bacaraton.Kaplan JE, Masur H, Holmes KK. [2007] Guidelines forpreventing opportunistic infections among HIV-infected persons. CDC; 51:1-23.

Published

2021-06-10

How to Cite

Trasia, R. F. (2021). C Current Treatment and Primary Prophylaxis for Toxoplasmosis. Journal Pharmaceutical Care and Sciences, 1(2), 132–135. https://doi.org/10.33859/jpcs.v2i1.73