E Effectiveness of Antihypertensive Therapy in Hypertensive Crisis Cases at the Emergency Department of Ulin Hospital Banjarmasin

Authors

  • Evita Peron Yoewono Sari Mulia University
  • Rina Saputri
  • Rifa’atul Mahmudah

Keywords:

Blood pressure, Effectiveness, Hypertensive Crissis, Urgency hypertension, Emergency hypertension

Abstract

ABSTRACT

Background: Hypertension crisis is a case of disease that often occurs, if not handled properly will cause comlication and death. This study was conducted to determine effective therapies in dealing with hypertensive crises so as to minimize the occurrence of complication and death in patients experiencing hypertensive crises

Method: The research method is a prospective cohort. Data analysis using Pair T-Test and ANOVA, analytic analysis with evidence based medecine principles. Consists of 11 urgent hypertension samples and 9 emergency hypertension samples.

Results: The results of the study for the case of hypertension urgency there are 6 therapeutic groups including furosemide, nicardipine, amlodipine, candesartan + amlodipine, clonidine and furosemide + nicardipine, but the therapy used is not in accordance with the guidelines but there are 2 groups of therapies that can reduce blood pressure including furosemide + nicardipine and clonidine, while for the case of emergence hypertension, there are 5 groups of therapies including nicardipine, amlodipine + nicardipine, furosemide, furosemide + candesartan + amlodipine and furosemide + candesartan + amlodipine + clonidine, the result is that nicardipine is a therapy that is in accordance with the guideline and the therapy is in accordance with the guideline and is in accordance with the guideline therapeutic target in lowering blood pressure.

Conclusion: The use therapy is not in accordance with the guidelines for patients with hypertensive urgency cases, but is able to lower the patient’s blood pressure, whereas for patients with hypertensive emergencies the effective therapy is nicardipine.

 

Keywords: Blood Pressure, Effectiveness, Hypertensive Crisis, Urgency Hypertension, Emergency Hypertension.

References

Akmarawati, K. (2016) ‘Hubungan Patofisiologi Hipertensi Dan Hipertensi Renal’, Ilmiah Kedokteran, 5, pp. 15–25.

Anggara Dwi, F.H dan Prayitno N. (2013) 'Faktor-Faktor yang berhubungan dengan Tekanan darah di Puskesmas Telaga Murni Cikarang Barat. Jakarta: Program Studi Kesehatan Masyarakat STIKES MH. Thamrin. Jurnal Ilmiah Kesehatan.Vol 5/No. 1

Dewi, D. A. and A. (2018) ‘Bahan Ajar Teknologi Laboratorium Medik (TLM) Hemostasis’, Kementrian Kesehatan Republik Indonesia, Pusat Pendidikan Sumber Daya Manusia Kesehatan, Badan Pengembangan Dan Pemberdayaan Sumber Daya Manusia Kesehatan.

Haidar, A. (2019) ‘Hipertensi Pada Kehamilan.’, Herb-Medicinae, 2, pp. 4005–4008. Available at: https://core.ac.uk/download/pdf/234099598.pdf.

Kiki, A. M. (2013) ‘Hubungan Antara Perilaku Olahraga, Stress Dan Pola Makan Dengan Tingkat Hipertensi Pada Lanjut Usia Di Posyandu Lansia Kelurahan Gebang Putih Kecamatan Sukolilo Kota Surabaya Kiki’, Jurnal Promkes Universitas Airlangga Surabaya, 1, pp. 227–231. doi: 10.1109/ISSSTA.2008.47.

Mancia, G. et al.(2018) 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC), Journal of Hypertension. doi: 10.1097/HJH.0b013e3281fc975a.

Musyahida, R. A. (2016) ‘Studi Penggunaan Terapi Furosemid pada Pasien Penyakit Ginjal Kronik (PGK) Stadium V’.

Mutakin, A. A. and (2013) ‘Analisis Amlodipin Dalam Plasma Darah Dan Sediaan Farmasi’, Farmaka, 15, pp. 1–15.

Nurhikma, E., Wulaisfan, R. and Musdalipah, M. (2019) ‘Cost Effectiveness Kombinasi Antihipertensi Candesartan-Bisoprolol dan Candesartan-Amlodipin Pada Pasien Rawat Jalan Penderita Hipertensi’, Jurnal Profesi Medika : JurnalKedokteran dan Kesehatan, 13(2), pp. 54–61. doi: 10.33533/jpm.v13i2.1284.

Page, I. H., Corcoran, A. C. and Taylor, R. D. (2018) ‘Management of hypertension.’, Postgraduate medicine, 1(6), pp. 436–447. doi: 10.1080/00325481.1947.11691709.

Restadiamawati, D. G. F. and (2015) ‘Pengaruh Penggunaan Nifedipin Pada Penderita Hipertensi Terhadap Laju Aliran Saliva Dan Pembesaran Gingiva’, Media Medika Muda, 4(4), pp. 713–722.

Riskesdas, K. (2018) ‘Hasil Utama Riset Kesehata Dasar (RISKESDAS)’, Journal of Physics A: Mathematical and Theoretical, 44(8), pp. 1–200. doi: 10.1088/1751-8113/44/8/085201.

Utami, N., Hasmono, D. and Yusetyani, L. (2013) ‘Studi Penggunaan Calcium Channel Blocker (Ccb) Pada Pasien Stroke Hemorraghic’, Media Farmasi: Jurnal Ilmu Farmasi, 10(2), pp. 71–83. doi: 10.12928/mf.v10i2.1174.

Yogiantoro, M., 2010, Hipertensi Esensial, dalam Sudoyo, A.W., Setiyohadi, B., Alwi, I., Simadibrata, M., Setiati, S., Ilmu Penyakit Dalam, Edisi 5 Jilid 1, Penerbit FK UI, Jakarta, hal 1082-108

Published

2020-11-05

How to Cite

Yoewono, E. P., Saputri, R., & Mahmudah, R. (2020). E Effectiveness of Antihypertensive Therapy in Hypertensive Crisis Cases at the Emergency Department of Ulin Hospital Banjarmasin. Journal Pharmaceutical Care and Sciences, 1(1), 19–27. Retrieved from https://ejurnal.unism.ac.id/index.php/jpcs/article/view/34

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